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Article

Investigation of putative multisubtype hepatitis C virus infections in vivo by heteroduplex mobility analysis of core/envelope subgenomes.

Journal of virology - 1 Aug 2008

Li Hui, Thomassen Lisa V, Majid Ayaz, McMahon Brian J, Bruden Dana, McArdle Susan, Bano Nazneen, Chung Minjun, Carithers Robert L, Perkins James D, Sullivan Daniel G, Gretch David R

Abstract excerpt

The frequency that multiple different subtypes of hepatitis C virus (HCV) simultaneously infect a given individual is controversial. To address this question, heteroduplex mobility analysis (HMA) of portions of the HCV core and envelope 1 region was optimized for sensitive and specific detection of mixtures of HCV genomes of different genotype or subtype. Using the standard HCV genotyping approach of...

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Identifiers

PMID: 18495766
DOI: 10.1128/JVI.02220-07
PMCID: PMC2493306

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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