Influence of genetic background and gender on bladder function in the mouse.

doi:10.1016/j.autneu.2008.04.001

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Article

Influence of genetic background and gender on bladder function in the mouse.

Autonomic neuroscience : basic & clinical - 1 Jun 2008

Cornelissen Laura L, Misajet Blake, Brooks David P, Hicks Alexandra

Abstract excerpt

Genetically targeted animals are used throughout research to investigate the role genes play in biological function, including the lower urinary tract. Generation of transgenic mice involves backcrossing for successive generations. Parental strain background genes can interact with the mutated gene potentially affecting interpretation of the mutant phenotype. Differences in physiological phenotypes may also be...

Topics

Animals
Autonomic Nervous System
Female
Genotype
Male
Mice
Mice, Inbred BALB C
Mice, Inbred C57BL
Mice, Transgenic
Muscle Contraction
Muscle, Smooth
Phenotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Pressure

Reflex

Sex Characteristics

Sex Factors

Species Specificity

Urinary Bladder

Source

Open in PubMed

Identifiers

PMID: 18495551
DOI: 10.1016/j.autneu.2008.04.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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