Article
Establishment and characterization of a new cell line TC-YIK originating from argyrophil small cell carcinoma of the uterine cervix integrating HPV16 DNA.
Cancer - 1 May 1991
Ichimura H, Yamasaki M, Tamura I, Katsumoto T, Sawada M, Kurimura O, Furuyama J, Kurimura T
Abstract excerpt
A new cell line, designated TC-YIK, was established from YIK-1 tumor cells, derived from argyrophil small cell carcinoma (ASCC) of the uterine cervix, and serially heterotransplanted into nude mice, integrating human papillomavirus type 16 (HPV16) DNA. The population doubling time of TC-YIK was approximately 21.6 hours at the 119th subculture. Subcutaneous injection of 1 x 10(8) TC-YIK cells into nude mice...
Topics
- Animals
- Carcinoma, Small Cell
- Cell Line
- DNA Probes
- Female
- Humans
- Immunoblotting
- Immunohistochemistry
- Karyotyping
- Mice
- Mice, Nude