Otosclerosis: an autoimmune disease?

doi:10.1016/j.autrev.2009.03.009

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Article

Otosclerosis: an autoimmune disease?

Autoimmunity reviews - 1 Dec 2009

Karosi Tamás, Szekanecz Zoltán, Sziklai István

Abstract excerpt

OBJECTIVES: To review our current knowledge of the etiopathogenesis of otosclerotic bone remodeling including genetics, viral infection, autoimmunity and inflammation and to discuss disease pathogenesis with relevance for pharmacotherapy. SYSTEMATIC REVIEW METHODOLOGY: Relevant publications on the etiopathogenesis, molecular biology, genetics and histopathology of otosclerosis from 1984 to 2009 were analyzed....

Topics

Animals
Anti-Inflammatory Agents
Autoimmune Diseases
Collagen Type I
Collagen Type I, alpha 1 Chain
Comorbidity
Genetic Predisposition to Disease
Humans
Measles
Measles virus
Otosclerosis
Polymorphism, Genetic
Vitamin D

Source

Open in PubMed

Identifiers

PMID: 19318139
DOI: 10.1016/j.autrev.2009.03.009

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