Article
Arp2/3 complex and Mps3 are required for regulation of ribosome biosynthesis in the secretory stress response.
Yeast (Chichester, England) - 1 Apr 2017
Yabuki Yukari, Katayama Masako, Kodama Yushi, Sakamoto Akiko, Yatsuhashi Ayumi, Funato Kouichi, Mizuta Keiko
Abstract excerpt
Secretory defects cause transcriptional repression of ribosome biogenesis in Saccharomyces cerevisiae. However, the molecular mechanism underlying secretory defect-induced transcriptional repression of ribosome biogenesis remains to be fully elucidated. In this study, we demonstrated that the Arp2/3 complex was required for reduction of ribosome protein gene expression in response to defective secretion by...
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