Article
The prevalence of the G2019S and R1441C/G/H mutations in LRRK2 in German patients with Parkinson's disease.
European journal of neurology - 1 Jul 2008
Möller J C, Rissling I, Mylius V, Höft C, Eggert K M, Oertel W H
Abstract excerpt
BACKGROUND AND PURPOSE: The prevalence of the heterozygous G2019S and R1441C/G/H mutations in LRRK2 in patients with Parkinson's disease (PD) has shown a great variability depending on the sample population. Here we investigated the prevalence of these mutations in a large cohort of German PD patients (n = 1049). RESULTS: We observed heterozygous G2019S mutations in five patients with apparently sporadic...
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