Article
Quantification of subclonal distributions of recurrent genomic aberrations in paired pre-treatment and relapse samples from patients with B-cell chronic lymphocytic leukemia.
Leukemia - 1 Jul 2012
Knight S J L, Yau C, Clifford R, Timbs A T, Sadighi Akha E, Dréau H M, Burns A, Ciria C, Oscier D G, Pettitt A R, Dutton S, Holmes C C, Taylor J, Cazier J-B, Schuh A
Abstract excerpt
Genome-wide array approaches and sequencing analyses are powerful tools for identifying genetic aberrations in cancers, including leukemias and lymphomas. However, the clinical and biological significance of such aberrations and their subclonal distribution are poorly understood. Here, we present the first genome-wide array based study of pre-treatment and relapse samples from patients with B-cell chronic...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.