Matrix metalloproteinase 1 (MMP1) is associated with early-onset lung cancer.

doi:10.1158/1055-9965.EPI-07-2840

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Matrix metalloproteinase 1 (MMP1) is associated with early-onset lung cancer.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 May 2008

Sauter Wiebke, Rosenberger Albert, Beckmann Lars, Kropp Silke, Mittelstrass Kirstin, Timofeeva Maria, Wölke Gabi, Steinwachs Angelika, Scheiner Daniela, Meese Eckart, Sybrecht Gerhard, Kronenberg Florian, Dienemann Hendrik, Chang-Claude Jenny, Illig Thomas, Wichmann Heinz-Erich, Bickeböller Heike, Risch Angela

Abstract excerpt

Matrix metalloproteinases (MMP) play a key role in the breakdown of extracellular matrix and in inflammatory processes. MMP1 is the most highly expressed interstitial collagenase degrading fibrillar collagens. Overexpression of MMP1 has been shown in tumor tissues and has been suggested to be associated with tumor invasion and metastasis. Nine haplotype tagging and additional two intronic single nucleotide...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age of Onset

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Haplotypes

Share to Linkage Disequilibrium

Share to Logistic Models

Share to Lung Neoplasms

Share to Matrix Metalloproteinase 1

Share to Monte Carlo Method

Share to Smoking

Source

Open in PubMed

Identifiers

PMID: 18483334
DOI: 10.1158/1055-9965.EPI-07-2840

Genes

MMP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Matrix metalloproteinase 1 (MMP1) is associated with early-onset lung cancer.PMID 18483334Read ↗

Haplotypes in matrix metalloproteinase gene cluster on chromosome 11q22 contribute to the risk of lung cancer development and progression.Semantic proximity Read ↗

MMP1 rs1799750 single nucleotide polymorphism and lung cancer risk: a meta-analysis.Semantic proximity Read ↗

Genotypes and haplotypes of matrix metalloproteinase 1, 3 and 12 genes and the risk of lung cancer.Semantic proximity Read ↗

Matrix metalloproteinase-1 promoter polymorphism and lung cancer risk.Semantic proximity Read ↗

MMP1-1607 1G/2G polymorphism and lung cancer risk: a meta-analysis.Semantic proximity Read ↗

Current evidence on the relationship between five polymorphisms in the matrix metalloproteinases (MMP) gene and lung cancer risk: a meta-analysis.Semantic proximity Read ↗

Genetic screening of MMP1 as a potential pathogenic gene in chronic obstructive pulmonary diseaseSemantic proximity Read ↗

Polymorphism +17 C/G in matrix metalloprotease MMP8 decreases lung cancer risk.Semantic proximity Read ↗

A functional polymorphism (-1607 1G→2G) in the matrix metalloproteinase-1 promoter is associated with development and progression of lung cancer.Semantic proximity Read ↗

Polymorphisms of matrix metalloproteinases 1, 2, 3 and 9 and susceptibility to lung, breast and colorectal cancer in over 30,000 subjects.Semantic proximity Read ↗

A single nucleotide polymorphism in the matrix metalloproteinase-1 promoter enhances lung cancer susceptibility.Semantic proximity Read ↗

MMP-1 promoter polymorphism is associated with risk of radiation-induced lung injury in lung cancer patients treated with radiotherapy.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.