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Article

Haplotypes in matrix metalloproteinase gene cluster on chromosome 11q22 contribute to the risk of lung cancer development and progression.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Dec 2006

Sun Tong, Gao Yang, Tan Wen, Ma Sufang, Zhang Xuemei, Wang Yonggang, Zhang Qingrun, Guo Yongli, Zhao Dan, Zeng Changqing, Lin Dongxin

Abstract excerpt

PURPOSE: Matrix metalloproteinases (MMP) play important roles in cancer development and single nucleotide polymorphisms (SNP) in some MMP genes were shown to confer susceptibility to certain cancers. This study examined the association between genotypes and haplotypes in the MMP1-MMP3-MMP12 gene cluster and risk of lung cancer development and metastasis. EXPERIMENTAL DESIGN: A two-stage investigation was...

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Share to Chromosomes, Human, Pair 11
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17145822
DOI: 10.1158/1078-0432.CCR-06-0464

Genes

MMP1
MMP3
MMP12

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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