Article
gamma-Aminobutyric acidA receptor heterogeneity is increased by alternative splicing of a novel beta-subunit gene transcript.
Journal of neurochemistry - 1 Apr 1991
Bateson A N, Lasham A, Darlison M G
Abstract excerpt
DNA sequences encoding two variants of a novel gamma-aminobutyric acidA (GABAA) receptor beta subunit were isolated from an embryonic chicken whole-brain cDNA library and a chicken genomic library. The coding regions of these variants only differ from each other by the absence or presence of 12 bp in the region that encodes the presumed intracellular loop between transmembrane domains M3 and M4; the encoded...
Topics
- Animals
- Base Sequence
- Chickens
- Cloning, Molecular
- DNA
- DNA, Recombinant
- Genetic Variation
- Molecular Sequence Data
- RNA Splicing
- RNA, Messenger
- Receptors, GABA-A
