Molecular and electrophysiological characterization of a allelic variant of the rat alpha 6 GABAA receptor subunit.

doi:10.1016/0169-328x(92)90209-t

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Article

Molecular and electrophysiological characterization of a allelic variant of the rat alpha 6 GABAA receptor subunit.

Brain research. Molecular brain research - 1 Nov 1992

Angelotti T P, Tan F, Chahine K G, Macdonald R L

Abstract excerpt

A 1.45 kb DNA sequence encoding the rat alpha 6 GABAA receptor subunit (nucleotides 33-1483) was cloned from a Sprague-Dawley rat brain cDNA library by PCR amplification. Dideoxy sequencing of two individual clones revealed that the nucleotide sequence differed at only one basepair (T480-->G) fro...

Topics

Alleles
Animals
Base Sequence
Cloning, Molecular
Female
Gene Amplification
Genetic Variation
Ion Channels
Male
Molecular Sequence Data
Rats
Rats, Sprague-Dawley
Receptors, GABA-A

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