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Article

RNA editing of the GABA(A) receptor alpha3 subunit alters the functional properties of recombinant receptors.

Neuroscience research - 1 Apr 2009

Nimmich Mitchell L, Heidelberg Laura S, Fisher Janet L

Abstract excerpt

RNA editing provides a post-transcriptional mechanism to increase structural heterogeneity of gene products. Recently, the alpha3 subunit of the GABAA receptors has been shown to undergo RNA editing. As a result, a highly conserved isoleucine residue in the third transmembrane domain is replaced with a methionine. To determine the effect of this structural change on receptor function, we compared the GABA...

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Identifiers

PMID: 19367790
DOI: 10.1016/j.neures.2009.01.003
PMCID: PMC2775542

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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