Article
Cluster analysis of obesity and asthma phenotypes.
PloS one - 1 Jan 2012
Sutherland E Rand, Goleva Elena, King Tonya S, Lehman Erik, Stevens Allen D, Jackson Leisa P, Stream Amanda R, Fahy John V, Leung Donald Y M
Abstract excerpt
BACKGROUND: Asthma is a heterogeneous disease with variability among patients in characteristics such as lung function, symptoms and control, body weight, markers of inflammation, and responsiveness to glucocorticoids (GC). Cluster analysis of well-characterized cohorts can advance understanding of disease subgroups in asthma and point to unsuspected disease mechanisms. We utilized an hypothesis-free cluster...
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