Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Comparative genomic and phenomic analysis of Clostridium difficile and Clostridium sordellii, two related pathogens with differing host tissue preference.

BMC genomics - 10 Jun 2015

Scaria Joy, Suzuki Haruo, Ptak Christopher P, Chen Jenn-Wei, Zhu Yongzhang, Guo Xiao-Kui, Chang Yung-Fu

Abstract excerpt

BACKGROUND: Clostridium difficile and C. sordellii are two anaerobic, spore forming, gram positive pathogens with a broad host range and the ability to cause lethal infections. Despite strong similarities between the two Clostridial strains, differences in their host tissue preference place C. difficile infections in the gastrointestinal tract and C. sordellii infections in soft tissues. RESULTS: In this study,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Clostridioides difficile
Share to Genome, Bacterial

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genomics

Share to High-Throughput Nucleotide Sequencing

Share to Host Specificity

Share to Hydrogen-Ion Concentration

Share to Phylogeny

Share to Sequence Analysis, DNA

Source

Open in PubMed Open full text

Identifiers

PMID: 26059449
DOI: 10.1186/s12864-015-1663-5
PMCID: PMC4462011

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Comparative genomic and phenomic analysis of Clostridium difficile and Clostridium sordellii, two related pathogens with differing host tissue preference.PMID 26059449Read ↗

Systems biology approach to functionally assess the Clostridioides difficile pangenome reveals genetic diversity with discriminatory power.Semantic proximity Read ↗

Identification and Characterization of Clostridium sordellii Toxin Gene RegulatorSemantic proximity Read ↗

Phylogenomic analysis of the collagen-like BclA proteins in <i>Clostridioides difficile</i>Semantic proximity Read ↗

<i>Clostridioides difficile</i> exploits toxin-mediated inflammation to alter the host nutritional landscape and exclude competitors from the gut microbiotaSemantic proximity Read ↗

Phenotypic analysis of various Clostridioides difficile ribotypes reveals consistency among core processes.Semantic proximity Read ↗

First Comparative Analysis of Clostridium septicum Genomes Provides Insights Into the Taxonomy, Species Genetic Diversity, and Virulence Related to Gas GangreneSemantic proximity Read ↗

Elucidating the pleiotropic effects of clpC deletion in Clostridioides difficile: proteomic and phenotypic insights.Semantic proximity Read ↗

Phylogenomic analysis of the collagen-like BclA proteins in Clostridioides difficile.Semantic proximity Read ↗

Elucidating human gut microbiota interactions that robustly inhibit diverse Clostridioides difficile strains across different nutrient landscapesSemantic proximity Read ↗

Vaginal and Rectal Clostridium sordellii and Clostridium perfringens Presence Among Women in the United StatesSemantic proximity Read ↗

Functional genomics reveals that Clostridium difficile Spo0A coordinates sporulation, virulence and metabolism.Semantic proximity Read ↗

Emerging <i>Clostridioides difficile</i> ribotypes have divergent metabolic phenotypesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.