Article
In vitro susceptibility of genotypically distinct and clonal Clostridium difficile strains to oritavancin.
The Journal of antimicrobial chemotherapy - 1 Oct 2008
O'Connor Rachael, Baines Simon D, Freeman Jane, Wilcox Mark H
Abstract excerpt
OBJECTIVES: Clostridium difficile infection is a nosocomial disease of increasing importance. First-line treatment is limited to metronidazole or vancomycin. Oritavancin is a lipoglycopeptide with activity against Gram-positive bacteria, including drug-resistant pathogens. MICs of oritavancin, metronidazole and vancomycin for genotypically distinct C. difficile strains, including epidemic C. difficile PCR...
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