A Point Mutation in the Transcriptional Repressor PerR Results in a Constitutive Oxidative Stress Response in Clostridioides difficile 630Δ erm

Abstract excerpt

The intestinal pathogen Clostridioides difficile is one of the major challenges in medical facilities nowadays. In order to better combat the bacterium, detailed knowledge of its physiology is mandatory. C. difficile strain 630Δ erm was generated in a laboratory from the patient-isolated strain C. difficile 630 (H. A. Hussain, A. P. Roberts, and P. Mullany, J Med Microbiol 54:137–141, 2005,...

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