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Article

Structures of regulatory regions in the human cytochrome P-450scc (desmolase) gene.

European journal of biochemistry - 30 Jan 1991

Inoue H, Watanabe N, Higashi Y, Fujii-Kuriyama Y

Abstract excerpt

The mechanism of regulatory expression of human cytochrome P-450scc gene by cAMP was investigated in a transient expression system using Y-1 cells (mouse adrenal tumor cell line) and a chimeric DNA composed of the structural gene for bacterial chloramphenicol acetyltransferase and the 5' flanking upstream sequence of the cytochrome P-450scc (cholesterol desmolase) gene which was revealed to contain a DNA...

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PMID: 1847689
DOI: 10.1111/j.1432-1033.1991.tb15738.x

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