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Article

Characterization of placental transcriptional activation of the human gene for P450scc.

DNA and cell biology - 1 May 1995

Hum D W, Aza-Blanc P, Miller W L

Abstract excerpt

Steroid hormones, which are ubiquitous regulators of physiologic processes, are produced primarily in the adrenals, gonads, and placenta. Each steroidogenic cell type produces different steroids due to cell-specific expression of various steroidogenic enzymes, but all steroidogenesis is initiated by P450scc, the mitochondrial enzyme that converts cholesterol to pregnenolone. We previously showed the unique...

Topics

Base Sequence
Cells, Cultured
Cholesterol Side-Chain Cleavage Enzyme
Humans
Molecular Sequence Data
Mutation
Organ Specificity
Placenta
Promoter Regions, Genetic
Transcriptional Activation
Transfection

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 7748495
DOI: 10.1089/dna.1995.14.451

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7748495-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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