Article
Characterization of placental transcriptional activation of the human gene for P450scc.
DNA and cell biology - 1 May 1995
Hum D W, Aza-Blanc P, Miller W L
Abstract excerpt
Steroid hormones, which are ubiquitous regulators of physiologic processes, are produced primarily in the adrenals, gonads, and placenta. Each steroidogenic cell type produces different steroids due to cell-specific expression of various steroidogenic enzymes, but all steroidogenesis is initiated by P450scc, the mitochondrial enzyme that converts cholesterol to pregnenolone. We previously showed the unique...
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