Article
Cigarette smoking, carrier state of A or G allele of 46A>G and 79C>G polymorphisms of beta2-adrenergic receptor gene, and the risk of coronary artery disease.
Kardiologia polska - 1 Apr 2008
Zak Iwnoa, Sarecka-Hujar Beata, Krauze Jolanta
Abstract excerpt
BACKGROUND: Coronary artery disease (CAD) is a multifactorial disorder which results from the interactions between a number of genetic and non-genetic factors. Beta-adrenergic receptors are cell-surface receptors which activate adenylyl cyclase by coupling to G proteins. The 46A>G and 79C>G polymorphisms of the beta2-adrenergic receptor gene (ADRB2) have been associated with altered response to sympathetic...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
