Article
Molecular spectrum of beta-thalassemia mutations in Northwestern Iran.
Hemoglobin - 1 Jan 2008
Hosseinpour Feizi Mohammad A, Hosseinpour Feizi Abbas A, Pouladi Nasser, Haghi Mehdi, Azarfam Parvin
Abstract excerpt
Beta-thalassemia (beta-thal) is a hereditary autosomal disorder with decreased or absent beta-globin chain synthesis. This study was designed to identify the common and rare beta-thal mutations in the Azerbaijan provinces, Northwestern Iran, and to set up a prenatal diagnostic laboratory. One hundred unrelated patients with known beta-thal major and intermedia, registered with the thalassemia clinics in the...
Topics
- Female
- Humans
- Iran
- Male
- Mass Screening
- Molecular Epidemiology
- Mutation
- Polymerase Chain Reaction
- beta-Thalassemia