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Article

Association between p.Leu54Met polymorphism at the paraoxonase-1 gene and plantar fascia thickness in young subjects with type 1 diabetes.

Diabetes care - 1 Aug 2008

Gallego Patricia H, Craig Maria E, Duffin Anthony C, Bennetts Bruce, Jenkins Alicia J, Hofer Sabine, Lam Albert, Donaghue Kim C

Abstract excerpt

OBJECTIVE: In type 1 diabetes, plantar fascia, a collagen-rich tissue, is susceptible to glycation and oxidation. Paraoxonase-1 (PON1) is an HDL-bound antioxidant enzyme. PON1 polymorphisms have been associated with susceptibility to macro- and microvascular complications. We investigated the relationship between plantar fascia thickness (PFT) and PON1 gene variants, p.Leu54Met, p.Gln192Arg, and c.-107C>T, in...

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Source

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Identifiers

PMID: 18469206
DOI: 10.2337/dc07-2236
PMCID: PMC2494642

Genes

PON1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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