Expression signatures, barriers and beyond: the role of oxidative stress in murine colitis and human inflammatory bowel disease revisited.

Abstract excerpt

(Table is included in full-text article). Inflammatory bowel disease is triggered by, as yet, unknown factors in the background of a polygenic susceptibility. Recent technological advances have made it possible to unravel genetic etiology and transcriptomal signature patterns of such complex diseases. Combining murine models with patient-derived data has proven a powerful approach to understand early events of...

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