Article
Pathogenesis and biomarkers of carcinogenesis in ulcerative colitis.
Nature reviews. Gastroenterology & hepatology - 7 Jun 2011
Thorsteinsdottir Sigrun, Gudjonsson Thorkell, Nielsen Ole Haagen, Vainer Ben, Seidelin Jakob Benedict
Abstract excerpt
One of the most serious complications of ulcerative colitis is the development of colorectal cancer. Screening patients with ulcerative colitis by standard histological examination of random intestinal biopsy samples might be inefficient as a method of cancer surveillance. This Review focuses on the current understanding of the pathogenesis of ulcerative colitis-associated colorectal cancer and how this knowledge...
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