Article
Intestinal immunoregulation: lessons from human mendelian diseases.
Mucosal immunology - 1 Sept 2021
Charbit-Henrion Fabienne, Parlato Marianna, Malamut Georgia, Ruemmele Frank, Cerf-Bensussan Nadine
Abstract excerpt
The mechanisms that maintain intestinal homeostasis despite constant exposure of the gut surface to multiple environmental antigens and to billions of microbes have been scrutinized over the past 20 years with the goals to gain basic knowledge, but also to elucidate the pathogenesis of inflammatory bowel diseases (IBD) and to identify therapeutic targets for these severe diseases. Considerable insight has been...
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