Article
Host genetic influences on fetal susceptibility to murine cytomegalovirus after maternal or fetal infection.
The Journal of infectious diseases - 1 Feb 1991
Fitzgerald N A, Shellam G R
Abstract excerpt
Genetically determined resistance to murine cytomegalovirus is observed in adult mice and is mediated in part by genes of the H-2 complex, with the H-2k haplotype conferring resistance. This model was used to examine the effect of primary maternal infection on fetal outcome. The severity of fetal growth retardation and death after primary maternal infection on day 8 of pregnancy was found to be genetically...
Topics
- Animals
- Body Weight
- Brain
- Cytomegalovirus
- Cytomegalovirus Infections
- Disease Models, Animal
- Female
- Fetal Death
- Fetal Diseases
- Fetal Growth Retardation
- Genetic Predisposition to Disease
