Maternal influence on susceptibility of offspring to Brugia malayi infection in a murine model of filariasis.

doi:10.1016/0001-706x(94)90022-1

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Article

Maternal influence on susceptibility of offspring to Brugia malayi infection in a murine model of filariasis.

Acta tropica - 1 Dec 1994

Rajan T V, Bailis J M, Yates J A, Shultz L D, Greiner D L, Nelson F K

Abstract excerpt

We have used the severe combined immunodeficient C.B-17-scid/scid mouse to investigate the influences of maternal immune status and parasite burden on the susceptibility (or resistance) of offspring to infection with the human filarial parasite, Brugia malayi. C.B-17-scid/scid mice are permissive...

Topics

Alleles
Animals
Animals, Newborn
Brugia malayi
Female
Filariasis
Genetic Predisposition to Disease
Immunity, Maternally-Acquired
Male
Mice
Mice, SCID

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