Article
Genotypic susceptibility scores and HIV type 1 RNA responses in treatment-experienced subjects with HIV type 1 infection.
AIDS research and human retroviruses - 1 May 2008
Anderson Jeffrey A, Jiang Hongyu, Ding Xiao, Petch Leslie, Journigan Terri, Fiscus Susan A, Haubrich Richard, Katzenstein David, Swanstrom Ronald, Gulick Roy M
Abstract excerpt
This study compared the role of genotypic susceptibility scores (GSS) as a predictor of virologic response in a group (n = 234) of HIV-infected, protease inhibitor (PI)-experienced subjects. Two scoring methods [discrete genotypic susceptibility score (dGSS) and continuous genotypic susceptibility score (cGSS)] were developed. Each drug in the subject's regimen was given a binary susceptibility score using...
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