Article
Weighted phenotypic susceptibility scores are predictive of the HIV-1 RNA response in protease inhibitor-experienced HIV-1-infected subjects.
The Journal of infectious diseases - 1 Sept 2004
Swanstrom Ronald, Bosch Ronald J, Katzenstein David, Cheng Hailong, Jiang Hongyu, Hellmann Nicholas, Haubrich Richard, Fiscus Susan A, Fletcher Courtney V, Acosta Edward P, Gulick Roy M
Abstract excerpt
We analyzed retrospectively, by use of logistic regression, the role of the phenotypic susceptibility score (PSS) as a determinant of virologic outcome in a study of treatment-experienced human immunodeficiency virus (HIV) type 1-infected subjects. A model for PSS in which each drug was treated equally and scored as active or inactive was not predictive of HIV-1 RNA load (VL) suppression. However, weighting the...
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