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Article

Synergistic effects of hypofibrinolysis and genetic and acquired risk factors on the risk of a first venous thrombosis.

PLoS medicine - 6 May 2008

Meltzer Mirjam E, Lisman Ton, Doggen Carine J M, de Groot Philip G, Rosendaal Frits R

Abstract excerpt

BACKGROUND: Previously, we demonstrated that hypofibrinolysis, a decreased capacity to dissolve a blood clot as measured with an overall clot lysis assay, increases the risk of venous thrombosis. Here, we investigated the combined effect of hypofibrinolysis with established risk factors associate...

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Identifiers

PMID: 18462012
DOI: 10.1371/journal.pmed.0050097
PMCID: PMC2365975

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18462012-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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