The C-terminal third of UL42, a HSV-1 DNA replication protein, is dispensable for viral growth.

doi:10.1006/viro.1993.1304

Back to search

Article

The C-terminal third of UL42, a HSV-1 DNA replication protein, is dispensable for viral growth.

Virology - 1 Jun 1993

Gao M, DiTusa S F, Cordingley M G

Abstract excerpt

UL42 is the herpes simplex virus type 1 DNA polymerase (Pol) accessory protein and is required for viral DNA replication and growth. Previous results from this laboratory demonstrated that the N-terminal two thirds of the protein contains all of the biochemical activities of the protein which can...

Topics

Animals
Biological Transport
Cell Compartmentation
Cell Nucleus
DNA Replication
DNA, Viral
DNA-Directed DNA Polymerase
Exodeoxyribonucleases
Phenotype
Recombinant Fusion Proteins
Sequence Deletion
Simplexvirus
Vero Cells
Viral Proteins
beta-Galactosidase

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.