Article
Depressed activation of the lectin pathway of complement in hereditary angioedema.
Clinical and experimental immunology - 1 Jul 2008
Varga L, Széplaki G, Laki J, Kocsis A, Kristóf K, Gál P, Bajtay Z, Wieslander J, Daha M R, Garred P, Madsen H O, Füst G, Farkas H
Abstract excerpt
The possibility of simultaneous measurement of the classical pathway (CP), mannan-binding lectin (MBL)--lectin pathway (LP) and alternative pathway (AP) of complement activation by the recently developed Wielisa method allowed us to investigate the in vivo significance of the C1-inhibitor (C1INH) in three complement activation pathways. Functional activity of the CP, LP and AP were measured in the sera of 68...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.