Characterization of three different elements in the 5'-flanking region of the fibronectin gene which mediate a transcriptional response to cAMP.

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Article

Characterization of three different elements in the 5'-flanking region of the fibronectin gene which mediate a transcriptional response to cAMP.

The Journal of biological chemistry - 15 Jan 1991

Bowlus C L, McQuillan J J, Dean D C

Abstract excerpt

A cAMP regulatory element (CRE) at nucleotide position -170 of the fibronectin gene was characterized previously (Dean, D. C., Blakeley, M. S., Newby, R. F., Ghazal, P., Hennighausen, L., and Bourgeois, S. (1989) Mol. Cell. Biol. 9, 1498-1506). Here we identify two additional low affinity CREs at...

Topics

Base Sequence
Binding, Competitive
Cyclic AMP
Electrophoresis, Polyacrylamide Gel
Fibroblasts
Fibronectins
Genes, Regulator
Humans
Molecular Sequence Data
Mutation
Nuclear Proteins
Peptide Mapping
Plasmids
Transcription, Genetic
Trypsin

Source

Open in PubMed

Identifiers

PMID: 1845987

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1845987-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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