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Article

Serotonin transporter polymorphisms and clinical response to sertraline across ethnicities.

Progress in neuro-psychopharmacology & biological psychiatry - 1 Jul 2006

Ng Chee Hong, Easteal Simon, Tan Susan, Schweitzer Isaac, Ho Brian Kong Wai, Aziz Salina

Abstract excerpt

The aim of this pilot study was to examine the relationship between clinical response, adverse effects, sertraline (SERT) plasma concentrations and the genetic polymorphism of the serotonin transporter gene-linked polymorphic region (5HTTLPR) in 2 ethnic patient groups. The study involved 45 patients in a clinical trial who received a fixed dose regimen of 50 mg SERT for one week, then a variable-dose regimen for...

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Identifiers

PMID: 16580768
DOI: 10.1016/j.pnpbp.2006.02.015

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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