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Article

Refinement of 2q and 7p loci in a large multiplex NTD family.

Birth defects research. Part A, Clinical and molecular teratology - 1 Jun 2008

Stamm Demetra S, Siegel Deborah G, Mehltretter Lorraine, Connelly Jessica J, Trott Alison, Ellis Nathen, Zismann Victoria, Stephan Dietrich A, George Timothy M, Vekemans Michel, Ashley-Koch Allison, Gilbert John R, Gregory Simon G, Speer Marcy C

Abstract excerpt

BACKGROUND: NTDs are considered complex disorders that arise from an interaction between genetic and environmental factors. NTD family 8776 is a large multigenerational Caucasian family that provides a unique resource for the genetic analysis of NTDs. Previous linkage analysis using a genome-wide SNP screen in family 8776 with multipoint nonparametric mapping methods identified maximum LOD* scores of...

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PMID: 18452155
DOI: 10.1002/bdra.20462

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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