Article
Fine mapping of the 2p11 dyslexia locus and exclusion of TACR1 as a candidate gene.
Human genetics - 1 Apr 2004
Peyrard-Janvid Myriam, Anthoni Heidi, Onkamo Päivi, Lahermo Päivi, Zucchelli Marco, Kaminen Nina, Hannula-Jouppi Katariina, Nopola-Hemmi Jaana, Voutilainen Arja, Lyytinen Heikki, Kere Juha
Abstract excerpt
Developmental dyslexia, or reading disability, is a multigenic complex disease for which at least five loci, i.e. DYX1-3 and DYX5-6, have been clearly identified from the human genome. To date, DYX1C1 is the only dyslexia candidate gene cloned. We have previously reported linkage to 2p11 and 7q32 in 11 Finnish pedigrees. Here, we report the fine mapping of the approximately 40-cM linked region from chromosome 2...
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