Article
Detection of EGFR gene mutations using the wash fluid of CT-guided biopsy needle in NSCLC patients.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer - 1 May 2008
Otani Hiroki, Toyooka Shinichi, Soh Junichi, Yamamoto Hiromasa, Suehisa Hiroshi, Kobayashi Naruyuki, Gobara Hideo, Mimura Hidefumi, Kiura Katsuyuki, Sano Yoshifumi, Kanazawa Susumu, Date Hiroshi
Abstract excerpt
INTRODUCTION: In this study, we examined whether epidermal growth factor receptor (EGFR) mutations were detectable using a polymerase chain reaction-based assay and wash fluid of computed tomography (CT)-guided lung biopsy needles. METHODS: DNA was extracted from wash fluid of CT-guided biopsy needles of 53 lung tumors (as diagnosed according to the results of the CT-guided biopsies). EGFR mutations, specifically...
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