Article
Using the genome to dissect the molecular basis of drug resistance.
Future microbiology - 1 Aug 2006
Kidgell Claire, Winzeler Elizabeth A
Abstract excerpt
The need to understand the genetic basis of drug resistance in human pathogens has never been greater. The global incidence of drug-resistant organisms, such as those that cause malaria, continues to rise, while the repertoire of effective, inexpensive drugs is declining. Genomic technologies, such as DNA microarrays and full-genome sequencing offer new hope in advancing our understanding of the underlying...
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