Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Nhp6p and Med3p regulate gene expression by controlling the local subunit composition of RNA polymerase II.

Journal of molecular biology - 30 May 2008

Xue Xiaowei, Lehming Norbert

Abstract excerpt

Nhp6p is an architectural Saccharomyces cerevisiae non-histone chromosomal protein that bends DNA and plays an important role in transcription and genome stability. We used the split-ubiquitin system to isolate proteins that interact with Nhp6p in vivo, and we confirmed 11 of these protein-protei...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adaptor Proteins, Signal Transducing
Share to Chromosomes
Share to Gene Expression Regulation, Fungal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mediator Complex

Share to Protein Subunits

Share to Proto-Oncogene Proteins c-myc

Share to RNA Polymerase II

Share to Ubiquitin

Source

Identifiers

PMID: 18448120
DOI: 10.1016/j.jmb.2008.03.069

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18448120-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Nhp6p and Med3p regulate gene expression by controlling the local subunit composition of RNA polymerase II.PMID 18448120Read ↗

A novel role for Nhp6 proteins in histone gene regulation in Saccharomyces cerevisiae.Semantic proximity Read ↗

Chromatin-mediated transcriptional regulation by the yeast architectural factors NHP6A and NHP6B.Semantic proximity Read ↗

Mutations in the yeast Nhp6 protein can differentially affect its in vivo functions.Semantic proximity Read ↗

Gene dosage affects the expression of the duplicated NHP6 genes of Saccharomyces cerevisiae.Semantic proximity Read ↗

TATA-binding protein mutants that are lethal in the absence of the Nhp6 high-mobility-group protein.Semantic proximity Read ↗

Identification of Uhp1, a ubiquitinated histone-like protein, as a target/mediator of Rhp6 in mating-type silencing in fission yeast.Semantic proximity Read ↗

Structural Basis of Plant Homeodomain Finger 6 (PHF6) Recognition by the Retinoblastoma Binding Protein 4 (RBBP4) Component of the Nucleosome Remodeling and Deacetylase (NuRD) ComplexSemantic proximity Read ↗

Histone-dependent association of Tup1-Ssn6 with repressed genes in vivo.Semantic proximity Read ↗

Novel E3 ubiquitin ligases that regulate histone protein levels in the budding yeast Saccharomyces cerevisiae.Semantic proximity Read ↗

Solution structure of the HMG protein NHP6A and its interaction with DNA reveals the structural determinants for non-sequence-specific binding.Semantic proximity Read ↗

PHF6 Interacts with the Nucleosome Remodeling and Deacetylation (NuRD) ComplexSemantic proximity Read ↗

Nhp6, an HMG1 protein, functions in SNR6 transcription by RNA polymerase III in S. cerevisiae.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.