Article
Experimental manipulation of immune-mediated disease and its fitness costs for rodent malaria parasites.
BMC evolutionary biology - 30 Apr 2008
Long Gráinne H, Chan Brian H K, Allen Judith E, Read Andrew F, Graham Andrea L
Abstract excerpt
BACKGROUND: Explaining parasite virulence (harm to the host) represents a major challenge for evolutionary and biomedical scientists alike. Most theoretical models of virulence evolution assume that virulence arises as a direct consequence of host exploitation, the process whereby parasites convert host resources into transmission opportunities. However, infection-induced disease can be immune-mediated...
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