Article
Immune-mediated competition in rodent malaria is most likely caused by induced changes in innate immune clearance of merozoites.
PLoS computational biology - 1 Jan 2014
Santhanam Jayanthi, Råberg Lars, Read Andrew F, Savill Nicholas Jon
Abstract excerpt
Malarial infections are often genetically diverse, leading to competitive interactions between parasites. A quantitative understanding of the competition between strains is essential to understand a wide range of issues, including the evolution of virulence and drug resistance. In this study, we use dynamical-model based Bayesian inference to investigate the cause of competitive suppression of an avirulent clone...
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