An inducible transgene expression system for regulated phenotypic modification of human embryonic stem cells.

doi:10.1089/scd.2007.0114

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Article

An inducible transgene expression system for regulated phenotypic modification of human embryonic stem cells.

Stem cells and development - 1 Apr 2008

Fu Ji-Dong, Jung Yunjoon, Chan Camie W, Li Ronald A

Abstract excerpt

Self-renewing pluripotent human embryonic stem (hES) cells are capable of regenerating such non-dividing cells as neurons and cardiomyocytes for therapies and can serve as an excellent experimental model for studying early human development. Both the spatial and temporal relationships of gene expression play a crucial role in determining differentiation; to obtain a better understanding of hES cell...

Topics

Animals
Cell Differentiation
Cells, Cultured
Cloning, Molecular
Dose-Response Relationship, Drug
Doxycycline
Electrophysiology
Embryonic Stem Cells
Gene Expression Regulation
Green Fluorescent Proteins
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Membrane Potentials

Mice

Models, Biological

Phenotype

Potassium Channels, Inwardly Rectifying

Transgenes

Source

Open in PubMed

Identifiers

PMID: 18447646
DOI: 10.1089/scd.2007.0114

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