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Article

STAT3 but Not STAT1 Is Required for Astrocyte Differentiation

23 Jan 2014

Abstract excerpt

The JAK-STAT signaling pathway has been implicated in astrocyte differentiation. Both STAT1 and STAT3 are expressed in the central nervous system and are thought to be important for glial differentiation, as mainly demonstrated in vitro; however direct in vivo evidence is missing. We investigated whether STAT1 and STAT3 are essential for astrocyte development by testing the STAT responsiveness of astrocyte...

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PMID: 24466267
DOI: 10.1371/journal.pone.0086851

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Related research

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STAT3 but Not STAT1 Is Required for Astrocyte DifferentiationPMID 24466267Read ↗

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