Article
Phenotypic transcription factors epigenetically mediate cell growth control.
Proceedings of the National Academy of Sciences of the United States of America - 6 May 2008
Ali Syed A, Zaidi Sayyed K, Dacwag Caroline S, Salma Nunciada, Young Daniel W, Shakoori Abdul R, Montecino Martin A, Lian Jane B, van Wijnen Andre J, Imbalzano Anthony N, Stein Gary S, Stein Janet L
Abstract excerpt
Ribosomal RNA (rRNA) genes are down-regulated during osteogenesis, myogenesis, and adipogenesis, necessitating a mechanistic understanding of interrelationships between growth control and phenotype commitment. Here, we show that cell fate-determining factors [MyoD, myogenin (Mgn), Runx2, C/EBPbet...
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