Article
Bipolar disorder in the Bulgarian Gypsies: genetic heterogeneity in a young founder population.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Mar 2009
Kaneva Radka, Milanova Vihra, Angelicheva Dora, MacGregor Stuart, Kostov Christian, Vladimirova Rositza, Aleksiev Spiridon, Angelova Mina, Stoyanova Vessela, Loh Angeline, Hallmayer Joachim, Kalaydjieva Luba, Jablensky Assen
Abstract excerpt
We report the results of follow-up analyses of 12 genomic regions showing evidence of linkage in a genome-wide scan (GWS) of Gypsy families with bipolar affective disorder (BPAD). The Gypsies are a young founder population comprising multiple genetically differentiated sub-isolates with strong founder effect and limited genetic diversity. The BPAD families belong to a single sub-isolate and are connected by...
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