Article
COQ2 and SNCA polymorphisms interact with environmental factors to modulate the risk of multiple system atrophy and subtype disposition.
European journal of neurology - 1 Oct 2022
Kuo Ming-Che, Lu Ying-Che, Tai Chun-Hwei, Soong Bing-Wen, Hu Fu-Chang, Chen Meng-Ling, Lin Chin-Hsien, Wu Ruey-Meei
Abstract excerpt
BACKGROUND AND PURPOSE: Multiple system atrophy (MSA) has no definitive genetic or environmental (G-E) risk factors, and the integrated effect of these factors on MSA etiology remains unknown. This study was undertaken to investigate the integrated effect of G-E factors associated with MSA and its subtypes, MSA-P and MSA-C. METHODS: A consecutive case-control study was conducted at two medical centers, and the...
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