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Article

A novel method for assessing sex-specific and genotype-specific response to injury in astrocyte culture.

Journal of neuroscience methods - 30 Jun 2008

Liu Mingyue, Oyarzabal Esteban A, Yang Rui, Murphy Stephanie J, Hurn Patricia D

Abstract excerpt

Female astrocytes sustain less cell death from oxygen-glucose deprivation (OGD) than male astrocytes. Arimidex, an aromatase inhibitor, abolishes these sex differences. To verify sex-dependent differences in P450 aromatase function in astrocyte cell death following OGD, we developed a novel metho...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 18436308
DOI: 10.1016/j.jneumeth.2008.03.002
PMCID: PMC2701697

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18436308-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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