Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Protection with estradiol in developmental models of apoptotic neurodegeneration

27 Jul 2005

Abstract excerpt

Medical measures that bear no known danger for the adult brain may trigger active neuronal death in the developing brain. Pharmacological blockade of N-methyl-D-aspartate or activation of GABA(A) receptors, blockade of voltage-dependent sodium channels, and oxygen induce widespread apoptotic neurodegeneration during the period of rapid brain growth in rodents. Because such measures are often necessary in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anesthesia and Neurotoxicity Research
Share to Intensive Care Unit Cognitive Disorders
Share to Neuroscience and Neuropharmacology Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 16049923
DOI: 10.1002/ana.20553

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Protection with estradiol in developmental models of apoptotic neurodegenerationPMID 16049923Read ↗

Drug‐induced Apoptotic Neurodegeneration in the Developing BrainSemantic proximity Read ↗

Neonatal anesthesia and dysregulation of the epigenomeSemantic proximity Read ↗

Neurodegeneration induced by general anaesthetics in the developing brain : mechanism and preventionSemantic proximity Read ↗

Protective Effects of Estrogen and Selective Estrogen Receptor Modulators in the Brain1Semantic proximity Read ↗

Vitamin E protects developing rat hippocampus and cerebellum against ethanol-induced oxidative stress and apoptosis [Erratum: 2009 May 15, v. 114, no. 2, p. 696.]Semantic proximity Read ↗

Sex Differences in Mechanisms and Outcome of Neonatal Hypoxia-Ischemia in Rodent Models: Implications for Sex-Specific Neuroprotection in Clinical Neonatal PracticeSemantic proximity Read ↗

Androgens predispose males to GABAA-mediated excitotoxicity in the developing hippocampus.Semantic proximity Read ↗

Vitamin E and β-carotene protect against ethanol combined with ischemia in an embryonic rat hippocampal culture model of fetal alcohol syndromeSemantic proximity Read ↗

Differential regulation of apoptosis-associated genes by estrogen receptor alpha in human neuroblastoma cellsSemantic proximity Read ↗

The investigation of the prenatal and postnatal alcohol exposure-induced neurodegeneration in rat brain: protection by betaine and/or omega-3Semantic proximity Read ↗

Ethanol-induced neuronal apoptosis in vivo requires BAX in the developing mouse brain.Semantic proximity Read ↗

Transient Blockade of ERK Phosphorylation in the Critical Period Causes Autistic Phenotypes as an Adult in Mice.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.