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Article

Early epithelial phenotypic changes predict graft fibrosis.

Journal of the American Society of Nephrology : JASN - 1 Aug 2008

Hertig Alexandre, Anglicheau Dany, Verine Jérôme, Pallet Nicolas, Touzot Maxime, Ancel Pierre-Yves, Mesnard Laurent, Brousse Nicole, Baugey Edith, Glotz Denis, Legendre Christophe, Rondeau Eric, Xu-Dubois Yi-Chun

Abstract excerpt

Chronic allograft nephropathy accounts for the loss of approximately 40% of allografts at 10 yr. Currently, no biomarker is available to detect interstitial fibrosis and tubular atrophy in the renal graft at an early stage, when intervention may be beneficial. Because tubular epithelial cells have been shown to exhibit phenotypic changes suggestive of epithelial-to-mesenchymal transition, we studied whether these...

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Identifiers

PMID: 18434568
DOI: 10.1681/ASN.2007101160
PMCID: PMC2488257

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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