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Article

Epithelial-to-Mesenchymal Transition in Early Transplant Tubulointerstitial Damage

14 May 2008

Abstract excerpt

It is unknown whether epithelial-to-mesenchymal transition (EMT) leads to tubulointerstitial fibrosis in renal transplants. In this study, interstitial fibrosis and markers of EMT were followed in protocol transplant biopsies in 24 patients. Tubulointerstitial damage (TID) increased from 34 to 54% between 1 and 3 mo after transplantation. Detection of EMT depended on the marker used; low levels of alpha-smooth...

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Share to Organ Transplantation Techniques and Outcomes
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PMID: 18480317
DOI: 10.1681/asn.2007050580

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