Article
Association study of the CFH Y402H polymorphism with Alzheimer's disease.
Neurobiology of aging - 1 Jan 2010
Le Fur Isabelle, Laumet Geoffroy, Richard Florence, Fievet Nathalie, Berr Claudine, Rouaud Olivier, Delcourt Cécile, Amouyel Philippe, Lambert Jean-Charles
Abstract excerpt
Several reports indicated that Alzheimer's disease (AD) and age-related macular degeneration (AMD) may share similar genetic and pathological features. We postulated that the functional Y402H polymorphism within the CFH gene and unambiguously recognised as a major genetic determinant of AMD, may also be a risk factor of AD. We analysed the association of this polymorphism with the AD risk in both prospective and...
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